One million success stories. Start yours today.

Head of Automated Small Molecule Synthesis (BOSTON)

Date Posted: Jun 28, 2026
Yearly: USD 177000.00 - USD 278080.00
Apply Now

Job Detail

  • location_on
    Location Cambridge, Massachusetts, United States of America
  • desktop_windows
    Job Type: Permanent
  • schedule
    Shift:
  • analytics
    Career Level:
  • group
    Positions:
  • calendar_view_day
    Experience:
  • male
    Gender: No Preference
  • school
    Degree:
  • calendar_month
    Apply Before: Sep 26, 2026
Email to Friend Add to Favourite Report Abuse

Job Description

Overview

The Head of Automated Small Molecule Synthesis at Takeda Pharmaceutical is a key leadership role based in Cambridge, MA, within the R&D division. This position focuses on advancing Takeda's Digital Discovery & Development Engine by leading automation initiatives in small molecule synthesis, leveraging AI and advanced technologies to enhance drug discovery processes.

Key responsibilities

  • Define and execute the automation strategy for small-molecule synthesis.
  • Promote the adoption of automated approaches across the research community.
  • Establish closed-loop DMTA vision by integrating robotics and AI/ML.
  • Design end-to-end automated workflows for synthesis and purification.
  • Continuously evaluate and integrate new technologies for enhanced synthesis capabilities.
  • Track and report key performance indicators related to workflow efficiency.
  • Drive reliability engineering and ensure compliance with EHS and safety standards.
  • Contribute to patents, publications, and activities that highlight platform advancements.
  • Engage in data governance practices that promote learning across research portfolios.

Required skills

  • Ph.D. in Organic or Medicinal Chemistry or equivalent experience.
  • 10+ years in pharmaceutical or biotech R&D, including small-molecule discovery.
  • Expertise in medicinal chemistry and cheminformatics.
  • Experience in building and scaling lab automation and R&D teams.
  • Proficiency with automated synthesis platforms and AI-driven DMTA.
  • Familiarity with LIMS/ELN and scheduling software.
  • Strong leadership and communication skills.

What the company offers

  • U.S. Base Salary Range: $177,000.00 - $278,080.00.
  • Eligibility for short-term and long-term incentives.
  • Medical, dental, and vision insurance.
  • 401(k) plan with company match.
  • Tuition reimbursement program.
  • Paid volunteer time off and company holidays.
  • Up to 80 hours of sick time and up to 120 hours of paid vacation.

Skills Required

Company Overview

Takeda Pharmaceutical
Cambridge, Massachusetts, United States of America
24 Current Jobs Openings

Takeda Pharmaceutical is a global biopharmaceutical company committed to bringing better health and a brighter future to people worldwide. We focus on developing innovative medicines based on profound science and patients' needs, actively engaging in... Read More

Google Map

Related Jobs