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Senior Director, AIRx Discovery Biology Lead (BOSTON)

Date Posted: Jun 28, 2026
Yearly: USD 212000.00 - USD 333190.00
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Job Detail

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    Location Cambridge, Massachusetts, United States of America
  • desktop_windows
    Job Type: Permanent
  • schedule
    Shift:
  • analytics
    Career Level:
  • group
    Positions:
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    Experience:
  • male
    Gender: No Preference
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    Degree:
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    Apply Before: Sep 26, 2026
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Job Description

Overview

The Senior Director, AIRx Discovery Biology Lead at Takeda Pharmaceutical will be pivotal in guiding drug discovery efforts through the integration of biology and AI-driven methodologies. This role entails overseeing the mechanistic foundations for programs within the AIRx portfolio and ensuring strategic alignment from target validation to clinical hypotheses.

Key responsibilities

  • Own disease biology and target validation strategy for the AIRx portfolio
  • Define translational biomarker strategies for clinical development
  • Design and oversee CRO-executed in vitro and in vivo biology studies
  • Integrate biology data into AI-enabled DMTA cycles
  • Challenge scientific assumptions to uphold biological integrity
  • Represent biology perspectives at Takeda governance forums
  • Stay updated with disease biology and competitive landscape
  • Shape biology practices within the AIRx model

Required skills

  • PhD in cell biology, molecular biology, pharmacology, or related discipline
  • 12-15+ years of drug discovery experience
  • Proven contributions to IND filings and IND-enabling biology packages
  • Experience in managing externalized CRO biology programs
  • Ability to connect target biology to clinical strategy
  • AI/ML data integration experience
  • Excellent cross-functional collaboration skills
  • Experience in at least one therapeutic area within Takeda Research portfolio

What the company offers

  • Base salary range: $212,000.00 - $333,190.00
  • Eligibility for short-term and long-term incentives
  • Medical, dental, vision insurance, 401(k) plan with company match
  • Paid volunteer time off and company holidays
  • Sick time and paid vacation accrual

Skills Required

Company Overview

Takeda Pharmaceutical
Cambridge, Massachusetts, United States of America
24 Current Jobs Openings

Takeda Pharmaceutical is a global biopharmaceutical company committed to bringing better health and a brighter future to people worldwide. We focus on developing innovative medicines based on profound science and patients' needs, actively engaging in... Read More

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